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通过对单次静脉注射氯胺酮（Ｋｅｔ）的定量脑电图（ｑＥＥＧ）分析，探求反应其麻醉状态的指标。９例患者予Ｋｅｔ４ｍｇ／ｋｇ单次静脉注射，分麻醉前、Ｋｅｔ静注后５ｍｉｎ、２０ｍｉｎ（初醒）３个时段做ｑＥＥＧ监测。结果相对功率（ＲＥＬ）麻醉前各导联均以α波为主，θ波成分最小。但给药后５ｍｉｎ却完全以θ波为主，至２０ｍｉｎ后θ波仍占主导。θ比率麻醉前较低，给药后５ｍｉｎ骤升，２０ｍｉｎ时并无明显回落。而反θ比率在给药５ｍｉｎ时骤降，２０ｍｉｎ时仍未回升。δ比率给药５ｍｉｎ后显著上升（Ｐ＜０．０１），２０ｍｉｎ时比率回落，其中Ｆ７、Ｆ８导联已与术前差异无显著性意义。结果表明持久、高功率的θ波是单次静注ｋｅｔ麻醉的特征表现；δ比率能反映从麻醉至初醒的变化趋势；而θ比率与反θ比率能更确切地反映Ｋｅｔ的麻醉状态。
Through a single intravenous injection of ketamine (Ket) Quantitative Electroencephalography (qEEG) analysis, to explore indicators of their anesthetic status. Nine patients were given a single intravenous injection of Ket4mg / kg, before anesthesia, Ket intravenous injection 5min, 20min (waking) three times to do qEEG monitoring. Results Relative power (REL) Before induction, each lead was dominated by α wave and θ wave was the smallest. But 5min after administration is completely based on theta-wave, theta-wave is still dominant after 20min. θ ratio lower before anesthesia, 5min after administration of sudden rise, 20min did not significantly drop. The anti-theta ratio dips when administered 5min, 20min did not rise. δ ratio increased significantly after 5 min (P <0.01), and the ratio decreased after 20 min. There was no significant difference between F7 and F8 lead and preoperative. The results showed that the long-lasting, high-power θ-wave was characteristic of a single intravenous ketorrhea; the δ-ratio reflected the change trend from anesthesia to early-wake; and the θ-ratio and anti-θ-ratio reflected the Ket anesthesia more accurately.