目前 ,临床常用的枸橼酸盐制剂中枸橼酸盐的含量测定多采用离子交换法 ,检测费时 ,操作较为繁锁。有报道采用ｐＨ指示剂吸收度比值法测定枸橼酸盐的含量[1] ,但是此方法只适用于含单一成分的制剂。笔者根据枸橼酸盐可与铜离子生成稳定络合物 ,且在紫外光区有特定吸收波长的原理 At present, the commonly used citrate preparations in the determination of citrate content using ion exchange method, testing time-consuming, more complicated operation. Reported the use of pH indicator absorbance ratio method for the determination of citrate content [1], but this method is only applicable to single-component formulations. The author based on citrate with copper ions can generate stable complexes, and in the UV region has a specific absorption wavelength principle