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目的探讨学龄前儿童不明原因一般中枢神经系统(CNS)症状发生现状及其可能的危险因素。方法通过问卷对青岛市黄岛区主要幼儿园720名3~6岁儿童进行调查,主要收集不良建筑物综合征(SBS)样症状、儿童个人信息、家庭住宅室内环境、幼儿园环境及室外环境等信息。结果被调查儿童不明原因CNS症状发生率为26.6%;多因素分析结果显示,三合板(OR=2.10,95%CI=1.30~3.41)、模压板家具(OR=2.45,95%CI=1.51~4.00)、靠近交通干道(OR=1.63,95%CI=1.04~2.54)、经常使用抗生素(OR=2.53,95%CI=1.47~4.35)及化学物质过敏(OR=1.14,95%CI=1.07~1.21)是不明原因CNS症状的危险因素,而湿拖把拖地(OR=0.45,95%CI=0.22~0.92)则是保护因素。结论学龄前儿童不明原因CNS症状发生率较高,家庭居室内家具材质、室内空气中的颗粒物质、交通污染、儿童自身疾病及过敏性体质是其可能的危险因素。
Objective To explore the status quo of presbyopia in children with unexplained central nervous system (CNS) symptoms and possible risk factors. Methods A total of 720 children from 3 to 6 years old in primary kindergarten in Huangdao District of Qingdao City were surveyed by questionnaire to collect information such as syndrome of poor building syndrome (SBS), personal information of children, indoor environment of family residence, kindergarten environment and outdoor environment . Results Multivariate analysis showed that the incidence of CNS symptoms was 26.6% in unknown children. Multivariate analysis showed that there was no significant difference in the incidence of CNS symptoms among children (OR = 2.10, 95% CI = 1.30 ~ 3.41) ), Close to the traffic artery (OR = 1.63, 95% CI = 1.04 ~ 2.54), antibiotics (OR = 2.53, 95% CI = 1.47-4.35) and chemical allergy (OR = 1.14, 95% CI = 1.21) were risk factors for unexplained CNS symptoms, whereas mop mopping (OR = 0.45, 95% CI = 0.22-0.92) was a protective factor. Conclusions The incidence of CNS symptoms in preschool children with unexplained causes is high. The materials of household furniture, indoor airborne particulate matter, traffic pollution, children’s own diseases and allergic constitution are the possible risk factors.