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于麻醉犬猫进行实验,发现酒石酸锑钠12mg/Kg 静脉注射能显著减弱下列数种循环反射:夹颈动脉与脾臓血管内注入烟碱所致的升压反射,电刺激迷走神神向中段所致的升压反射与降压反射。进一步分析证明,锑剂并不影响植物神经介质乙醯胆碱与肾上腺素的有关作用,也不影响迷走神经节与交感神经节以及它们节后纤维末梢的传导。因此,锑剂在以上循环反射的反射弧中,最大可能即作用于其中枢环节,即有关的皮质下中枢,此外对于肾上腺髓质的抑制作用亦有重要的意义。
In anesthetizing dogs and cats and found that intravenous sodium antimony tartrate 12mg / Kg significantly weakened the following several kinds of circulatory reflex: clip carotid artery and splenic blood vessels injected with nicotine into the blood pressure reflex, electrical stimulation vagus God to the middle Caused by the boost reflex and buck reflex. Further analysis showed that antimony does not affect the role of the autonomic mediator acetylcholine and epinephrine, and does not affect the conduction of vagal ganglia and sympathetic ganglia and their postnatal fiber tip. Therefore, the antimony agent in the above reflex arc arc, the greatest possible role that is its central part, that is, the relevant subcutaneous center, in addition to the inhibitory effect of adrenal medulla is also of great significance.