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目的:探讨老年人H型高血压血浆同型半胱氨酸(HCY)、与脉压(PP)的相关性。方法采用动态血压检测24h平均脉压(PP)水平,计算PP平均值,选择PP正常对照组(pp60mmHg)118例,检测Hcy水平。比较Hcy在两组间的差异及其相关性。结果 PP增高组Hcy水平(15.48±1.54),明显高于对照组(10.37±2.27)(<0.01),pp增高组高Hcy血症率68.64%,高于对照组34.31%。 Pearson相关分析显示平均脉压、平均收缩压与Hcy呈明显正相关。结论老年H型高血压患者Hcy水平与脉压呈正相关。“,”Objective To investigate the cor elation of plasma homocysteine (HCY) and pulse pressure (PP) in elderly patients with H-type hypertension.Methods 24h pulse pressure (PP) was monitored using ambulatory blood pressure and the mean was calculated. 102 patients with normal PP (PP60mmHg) were chosen andassigned to control and PP increasing groups, respectively. Their HCY levels were determined. The dif erence in HCY level was compared between the two groups and the correlation was studied.Results HCY level was significantly higher in PP increasing group (15.48±1.54) than that in control group (10.37±2.27) ( <0.01) The incidence of hyperhomocysteinemia was 68.64% in PP increasing group, significantly higher than the 34.31% in control group. Pearson analysis revealed significant positive cor elation between mean pulse pressure as wel as mean systolic pressure and HCY level. Conclusion HCY level is positively cor elated with pulse pressure in elderly patients with H-type hypertension.