神经纤维瘤病伴多发性颅骨缺损１例马百芳，陆庆国（山东省德州地区人民医院皮肤科２６３０１４）患者男性，２８岁。因面部、躯干发生柔软结节２０余年，近来加重就诊。自幼发现左颞部有一豆大柔软结节，背部有４个指甲大咖啡色斑，无痛痒。８年前此皮损渐扩大，增多，术... One case of neurofibromatosis with multiple skull defects MA Bai-fang, LU Qing-guo (Department of Dermatology, Dezhou People’s Hospital, Shandong Province 263014) The patient was male, 28 years old. Due to facial, torso soft nodules occurred more than 20 years, recently increased treatment. I found a large tender bean nodules in the left temporal part since childhood. There are 4 large nails on the back with no itchiness. 8 years ago, this lesion gradually expanded, increased, surgery ...