目的：报告扁平部玻璃体切割手术治疗黄斑裂孔、视网膜下新生血管膜及视网膜前膜，术后发生视野缺损的发生率，并探讨其发病机理。方法：所有病人于术后２个月后接受Ｇｏｌｄｍａｎｎ视野检查，术前影响视野的疾病如青光眼不包括在本研究中。临床资料包括诊断、术前术后视力、手术过程，以及术前术后眼压。结果：在４８例病人５０只眼中，共９只眼（１８％）术后发生视野缺损，其中黄斑裂孔组２１只眼中有４只眼（１９％），视网膜下新生血管膜组１３只眼中有５只眼（３８％），视网膜前膜组１６只眼术后均无视野缺损（ｐ＜０．０５）；视野损害与年龄及术前术后眼压无关。结论：玻璃体切割手术后视野缺损多发生在术中有气液交换的病例，气液交换过程中，在吸除视神经表面液体时，器械对视神经损伤是导致视野受损的可能原因 OBJECTIVE: To report the incidence of visual field defect and its pathogenesis in treatment of macular hole, subretinal neovascular membrane and pre-retinal membrane after pars plana vitrectomy. METHODS: All patients underwent Goldmann visual field examinations 2 months after surgery. Preoperative visual field disorders such as glaucoma were not included in this study. Clinical data including diagnosis, preoperative and postoperative visual acuity, surgical procedures, and preoperative and postoperative intraocular pressure. RESULTS: In 50 eyes of 48 patients, a total of 9 eyes (18%) underwent visual field defect after operation, of which 4 eyes (19%) of 21 eyes of macular hole group and 13 eyes of retinal neovascularization group There were no visual field defects in 5 eyes (38%) and 16 eyes of pre-retinal membrane group (p <0.05). The visual field damage was not related to age and preoperative and postoperative IOP. Conclusions: The visual field defects occurred during the operation of vitrectomy. In the process of gas-liquid exchange, the damage of the optic nerve to the optic nerve is the possible reason of visual field damage during the aspiration of the optic nerve surface fluid