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利用Wittig反应合成了一系列伪异胞苷类化合物,通过改进实验条件提高了关键中间体的收率,并深入研究了保护的核糖甲氧基丙烯酸乙酯与各种取代的胍和脒的缩合条件.
Wittig reaction was used to synthesize a series of pseudo-cytidine compounds. The yield of key intermediates was improved by improving the experimental conditions. The condensation of the protected ribose methoxyethyl acrylate with various substituted guanidines and amidines condition.