应用环丙沙星治疗急性非特异性前列腺炎52例和淋球菌性前列腺炎27例,剂量0.25g,0.5g或0.75g,q12h,po,3-9do总有效率76％,不良反应8％,用药量与临床效应和不良反应发生率呈正相关。该药0.1-10ng/mL的抑菌力呈线性相关(r=0.999);出现明显抑菌圈的浓度,在枯草芽孢杆菌和藤黄八叠球菌各为0.01ng/mL和0.3ng/mL,相当于诺氟沙星10ng/mL的抑菌力各为1.3ng/mL和1.8ng/mL。 Application of ciprofloxacin in the treatment of acute non-specific prostatitis in 52 cases and gonococcal prostatitis in 27 cases, the dose of 0.25g, 0.5g or 0.75g, q12h, po, 3-9do total effective rate 76%, adverse reactions 8% The dosage was positively correlated with the clinical effect and the incidence of adverse reactions. The antibacterial activity of the drug 0.1-10ng / mL showed a linear correlation (r = 0.999). The concentration of the antibacterial ring was obviously inhibited. The inhibitory concentrations were 0.01ng / mL and 0.3ng / mL for B. subtilis and N. luteus, The bacteriostatic power equivalent to norfloxacin 10 ng / mL was 1.3 ng / mL and 1.8 ng / mL, respectively.