应激性溃疡是指由严重创伤、烧伤、感染以及药物等因素引起的急性胃粘膜糜烂或溃疡,常并发大出血而威胁病人的生命。根据Desmond 的统计,应激性溃疡引起的大出血约占整个上消化道大出血的10%。自从70年代早期,纤维胃镜、胃内照相发明和广泛应用于临床以来,不仅提高了对此病的确诊率,而且大大提高了对应激性溃疡的认识。因此,很多医师都认为应激性溃疡这一名称并不能正确反映此病的病因和病理损害。首先从纤维胃镜可发现的胃粘膜病变而言,绝大多数是胃粘膜的浅表损害,从点状的分散 Stress ulcer is caused by severe trauma, burns, infections and drugs caused by acute gastric mucosal erosion or ulcer, often complicated by bleeding and threaten the patient’s life. According to Desmond statistics, severe bleeding caused by stress ulcer accounts for about 10% of the total upper gastrointestinal bleeding. Since the early 70s, fiber endoscopy, stomach imaging and widely used in clinical practice, not only increased the diagnosis of the disease rate, but also greatly raised the awareness of stress ulcer. Therefore, many doctors believe that the name of stress ulcer does not correctly reflect the etiology and pathological damage of the disease. First of all, from the gastroscopy can be found in gastric mucosal lesions, the vast majority of gastric mucosal superficial lesions, scattered from the point