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本文应用戊二醛化红血球凝集抑制试验测定188例不同类型肾脏病患者尿中FDP含量,结果表明儿童肾病全部阴性,对肾病诊断分型有鉴别意义。慢性肾炎尿毒症的FDP含量比普通型高,随着病情恶化,血肌酐,血尿素氮增加,尿FDP亦增加,因此尿FDP含量,可能反应肾功能损害程度。在慢性肾炎治疗过程中,临床症状缓解,肾功能恢复,尿FDP含量降低或阴转,如病情恶化,则FDP持续阳性或含量增加,因此对病情演变,疗效观察,有参考价值。 本组肾炎病人,同时测定血清,尿FDP含量者共61例,结果表明尿FDP阳性率明显高于血清FDP。后者取样方便,有利于动态观察。
In this paper, glutaraldehyde hemagglutination inhibition assay 188 cases of different types of renal disease in patients with urinary FDP content, the results show that all children with negative nephropathy, differential diagnosis of kidney disease has a differential significance. Chronic nephritis uremia FDP levels higher than common type, with the deterioration of the condition, serum creatinine, blood urea nitrogen increased urinary FDP also increased, so urinary FDP content may reflect the extent of renal damage. In the course of treatment of chronic nephritis, clinical symptoms, renal function recovery, urinary FDP content decreased or negative conversion, such as the deterioration of the condition, the FDP continued positive or increased, so the evolution of the disease, the efficacy of observation, a reference value. The group of nephritis patients, simultaneous determination of serum and urinary FDP content were a total of 61 cases, the results showed that urine FDP positive rate was significantly higher than serum FDP. The latter convenient sampling, is conducive to dynamic observation.