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在电镜下观察黄瓜花叶病毒（ＣＭＶ）的侵染扩散部位发现：病毒粒体入侵细胞及复制后子代粒体的扩散同烟草花叶病毒一样是以整体形式向细胞壁靠拢、附着，并通过胞间连丝进入易感细胞，同时还发现少量病毒粒体似有直接穿过胞壁入胞的现象．寄主植物在病毒入侵后，除了外观上出现病斑，叶片细胞的结构，尤其是叶绿体病变明显，如：外膜不完整、片层松散、结构肿胀，严重时会使整个叶绿体解体．另外，细胞质中还出现许多高尔基小囊泡等超微结构的影响．
Observed under electron microscopy of cucumber mosaic virus (CMV) spread of infection found that: virion invasive cells and replication of the progeny of the spread of the progeny of the same with the tobacco mosaic virus as a monolithic approach to the cell wall, attached, and through Mosaic silk into the susceptible cells, but also found that a small amount of virosomes like cells through the cell wall directly into the phenomenon. Host plant in the invasion of the virus, in addition to the appearance of spots, the structure of leaf cells, especially chloroplasts lesions, such as: the outer membrane is incomplete, lamellar loose, swollen structure, severe chlorophyll will disintegrate. In addition, there are many ultrastructural effects such as Golgi vesicles in the cytoplasm.