临床病理数据证明淋巴系统是实体性肿瘤转移的主要路径。然而,肿瘤内淋巴管生成对口腔癌预后的影响仍然不明,因为至今尚无可靠的淋巴管内皮标志物。本研究采用新的淋巴管内皮标志物PA2.26分析原发口腔癌患者肿瘤组织内淋巴管生成情况。方法作者调查研究了61例早期口腔癌患者手 Clinical pathology data show that the lymphatic system is the main path of solid tumor metastasis. However, the effect of intratumoral lymphangiogenesis on the prognosis of oral cancer remains unknown as there is no reliable lymphatic endothelial marker yet. In this study, a new lymphatic endothelial marker PA2.26 was used to analyze the lymphangiogenesis in the tumor tissues of primary oral cancer patients. Methods The authors investigated 61 patients with early stage oral cancer patients