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目的观察奥扎格雷钠治疗急性脑梗死患者,对偏瘫肢体近期运动功能的影响。方法采用前瞻性随机对照方法分为治疗组和对照组。治疗组63例,应用奥扎格雷钠静滴,对照组应用复方丹参静滴。以简式Fugl-Meyer(FMA)评分法,Barthel指数进行治疗前后功能评定。结果治疗组在肢体运动功能、ADL能力方面治疗后显著改善,与对照组相比差异显著(P<0.05)。结论常规剂量奥扎格雷钠对治疗脑梗死、促进偏瘫肢体功能恢复及提高ADL能力极为重要,而且比较安全。
Objective To observe the effect of ozagrel sodium on short-term motor function of hemiparetic limbs in patients with acute cerebral infarction. Methods A prospective randomized controlled trial was divided into treatment group and control group. The treatment group of 63 cases, the application of ozagrel sodium intravenous infusion, the control group of Compound Salvia intravenous infusion. The functional assessment was performed before and after treatment with the simple Fugl-Meyer (FMA) score and the Barthel index. Results The treatment group had significant improvement in motor function and ADL ability after treatment, which was significantly different from the control group (P <0.05). Conclusion Conventional doses of ozagrel sodium are very important and safe for the treatment of cerebral infarction, functional recovery of hemiparetic limbs and the ability to improve ADL.