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目的:分析2010~2016年解放军某医院输血不良反应的临床特点及影响因素,为进一步加强临床合理安全输血提供理论依据。方法:回顾性分析2010~2016年解放军某医院患者输血不良反应发生情况。结果:7年内共接受输血治疗患者163 812例,发生输血不良反应59例(0.036%);输注悬浮红细胞发生不良反应31例(52.54%),血浆25例(42.37%),血小板2例(3.39%),全血1例(1.69%)。创伤外科输血不良反应发生率最高,占0.17%,其次为神经内科(0.13%)、心血管内科(0.12%),妇产科(0.09%)和肿瘤科(0.08%),且内科输血不良反应发生率一般高于外科。结论:为保障临床安全用血,减少输血不良反应的发生,医护人员要加强输血前不规则抗体筛查等措施,全面监督管理输血链中各个环节的规范化。
Objective: To analyze the clinical characteristics and influencing factors of blood transfusion adverse reactions in a hospital of PLA from 2010 to 2016, and to provide a theoretical basis for further strengthening clinical safe blood transfusion. Methods: The incidence of adverse transfusion reactions in a hospital of People’s Liberation Army from 2010 to 2016 was retrospectively analyzed. Results: A total of 163 812 patients received transfusion therapy in 7 years, 59 (0.036%) were transfusion adverse reactions; 31 (52.54%) were adverse reactions in transfusion of erythrocytes, 25 (42.37%) were plasma and 2 3.39%), whole blood in 1 case (1.69%). The incidence of transfusion adverse reactions was highest in trauma surgery, accounting for 0.17%, followed by neurology (0.13%), cardiovascular (0.12%), obstetrics and gynecology (0.09%) and oncology (0.08%), The incidence is generally higher than surgery. Conclusion: In order to protect blood for clinical use and reduce adverse reactions of blood transfusion, medical staff should strengthen the screening of irregular antibodies before transfusion, and supervise the standardization of all aspects of blood transfusion chain.