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应用RT-PCR法在非甲~非戊型肝炎患者血清及单采浆站供血员血浆中检测到GBV-CRNA,扩增产物经序列测定进一步确证,在30例非甲~非戊型肝炎患者中阳性率为6.6%;在600例单采浆供血者血浆中阳性率为0.33%。提示GBV-C可能不是非甲~非戊型肝炎的主要致病因子,可能存在GBV-C健康携带者。
GBV-CRNA was detected by RT-PCR in the blood plasma of plasma of patients with non-hepatitis E and non-hepatitis E non-hepatitis E, and the amplified products were further confirmed by sequencing. Among 30 non-hepatitis E non-hepatitis E patients The positive rate was 6.6%. The positive rate of plasma in 600 plasma samples was 0.33%. It is suggested that GBV-C may not be the main causative agent of non-hepatitis E and non-hepatitis E, and GBV-C healthy carriers may exist.