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原代培养的人胚鼻咽上皮移植块和生长晕作原位包埋后观察,发现移植块的上皮大多发生鳞状上皮化生。在复层上皮细胞的胞浆内含有丰富的胞浆微丝和/或张力原纤维,表层细胞尤为明显;基底细胞的胞浆内除含张力原纤维外,尚有丰富的核蛋白体及少量扩张的内质网和数量不等的类粘原颗粒。生长晕的单层细胞形态多样,胞浆中多含数量不等的张力原纤维;有的同时含有扩张的内质网和类粘原颗粒。作者认为鳞状上皮化生是对环境变化的一种适应性反应。
Primary culture of human embryonic nasopharyngeal epithelial graft and growth halo for in situ embedding was observed and found that most epithelial metaplasia occurred squamous metaplasia. In the cytoplasm of the stratified epithelial cells is rich in cytoplasmic microfilaments and / or tension fibrils, especially in the surface cells; basal cell cytoplasm in addition to containing fibril fibers, there are a large number of ribosomes and a small amount Expanded endoplasmic reticulum and a variable number of class mucoid particles. Monolayer cells that grow dizzy are morphologically diverse, with cytoplasm containing a wide range of tension fibrils; some also contain expansible endoplasmic reticulum and adhesion-like particles. The authors suggest that squamous metaplasia is an adaptive response to environmental changes.