将可重复使用的CuO纳米粒子成功用于催化微波辅助的腈和NaN_3[3+2]环加成反应高效合成5-取代1H-四唑类化合物.该法突出特点为成本低、合成快、稳定性高、可重复使用、反应条件温和、无需任何添加物、官能团兼容性好和产率高.这种环境友好的微波辅助纳米粒子催化合成策略可望替代现有的涉及常规路易斯酸催化剂方法,以及作为一种简易的合成特殊化合物的方法. The reusable CuO nanoparticles were successfully used to catalyze the microwave-assisted nitrile and NaN_3 [3 + 2] cycloaddition reaction to efficiently synthesize 5-substituted 1H-tetrazole compounds.The outstanding features of this method are low cost, fast synthesis, High stability, reusable, mild reaction conditions without any additives, good functional group compatibility and high yield.The environmentally friendly microwave-assisted catalytic synthesis of nanoparticles is expected to replace the existing conventional Lewis acid catalyst method , As well as a simple method for the synthesis of special compounds.