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目的探讨在Ｂ型超声引导下，以无水酒精行肝癌局部注射对原发性肝癌的治疗作用。方法应用巢式逆转录多聚合酶链反应检测无水酒精局部注射治疗前后，肝癌患者周围静脉血液中ＡＦＰｍＲＮＡ变化。结果９例肝癌患者中术前有４例血液ＡＦＰｍＲＮＡ阳性（４／９）；无水酒精瘤内注射治疗３～５次后（２周），血液ＡＦＰｍＲＮＡ阳性者减至１例（１／９）。结论无水酒精瘤内注射治疗原发性肝癌可以预防或阻止肝癌远处器官转移的发生。
Objective To investigate the therapeutic effect of local injection of hepatocellular carcinoma with absolute alcohol on the primary liver cancer under the guidance of B-mode ultrasound. Methods Nested reverse transcription polymerase chain reaction (RT-PCR) was used to detect the change of AFP mRNA in peripheral blood of patients with hepatocellular carcinoma before and after local alcohol injection. Results There were 4 cases of blood AFPmRNA positive (4/9) before surgery in 9 cases of liver cancer patients; AFP mRNA positive cases were reduced to 1 case (1/9) after intravitreous injection of anesthesia for 3 to 5 times (2 weeks). . Conclusion The intratumoral injection of anhydrous alcohol to treat primary liver cancer can prevent or prevent the distant metastasis of liver cancer.