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目的探讨免疫球蛋白在肝病患者血清检测中的临床应用价值。方法对汕头大学医院第一附属医院于2009年1月—2010年4月收治的66例肝病患者的免疫球蛋白(IgG、IgA、IgM)进行分组检测,并与对照组进行对比分析。结果本文对四组患者的Ig水平测定后,进行统计学分析发现急性肝炎组患者的IgM水平要明显高于正常对照组,而其IgGI、gA水平与正常对照组相比则无明显差异。其次,慢性肝炎组患者的IgMI、gG水平均明显高于正常对照组,而IgA水平与正常对照组相比无明显差异。肝硬化组患者的IgA水平与正常对照组比较无明显差异(P>0.05),IgMI、gG均明显高于正常对照组。结论免疫球蛋白对于肝病的诊断有着重要临床应用价值。
Objective To investigate the clinical value of immunoglobulin in the serum detection of liver disease patients. Methods Immunoglobulin (IgG, IgA and IgM) in 66 patients with liver disease admitted to the First Affiliated Hospital of Shantou University Hospital from January 2009 to April 2010 were detected by grouping and compared with the control group. Results In the present study, IgM levels in patients with acute hepatitis were significantly higher than those in normal controls after the Ig levels were measured in the four groups. However, the levels of IgGI and gA in patients with acute hepatitis were not significantly different from those in normal controls. Second, the levels of IgMI and gG in patients with chronic hepatitis were significantly higher than those in normal controls, while the levels of IgA were not significantly different from those in normal controls. The levels of IgA in patients with cirrhosis were not significantly different from those in normal controls (P> 0.05). IgMI and gG in patients with cirrhosis were significantly higher than those in normal controls. Conclusion Immunoglobulin has important clinical value for the diagnosis of liver disease.