Objective:To explore natural compounds as potential inhibitors against main protease (Mpro) of SARS-CoV-2. Methods:In th......

以胡椒碱为起始原料,与KOH反应生成胡椒酸钾盐,经酸化后制得胡椒酸(2);2与乙醇经酯化反应制得胡椒酸乙酯(3);3与己二胺在金属钠催......

制备含不同渗透促进剂的止泻凝胶膏,采用Franz扩散池考察各处方的体外透皮行为。采用HPLC法测定制品中胡椒碱含量。结果表明,当促......