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目的探讨卒中相关性感染发生的危险因素,为临床防治卒中相关性感染提供一定的临床依据。方法通过文献资料及前期研究筛选出可能影响卒中相关性感染的因素,并制定病例调查表,对纳入的患者进行相关因素及卒中相关性感染是否发生进行多因素logistic回归分析。结果纳入病例中卒中相关性感染的发生率为18.75%,感染部位以肺部感染、泌尿系感染为主,logistic回归分析发现首次发病、意识障碍、合并糖尿病、血清IL-6水平升高、侵入性操作为卒中相关性感染的危险因素,差异均有显著性(P<0.05)。结论卒中相关性感染发生与多种因素相关,临床可根据危险因素是否存在而采取相关的预防措施以降低其发生率。
Objective To explore the risk factors of stroke-related infections and provide some clinical evidences for clinical prevention and treatment of stroke-associated infections. Methods According to the literature and previous studies, the factors that may affect the stroke-related infection were screened and the case-control questionnaires were made. Multivariate logistic regression analysis was performed on the related factors and the incidence of stroke-related infections. Results The incidence of stroke-associated infection was 18.75%. The infection was mainly pulmonary infection and urinary tract infection. Logistic regression analysis showed that the incidence of stroke, disturbance of consciousness, diabetes mellitus, elevated serum IL-6 level and invasion Sex-related risk factors for stroke-related infections were significantly different (P <0.05). Conclusions The incidence of stroke-related infections is related to many factors. In clinical practice, relevant preventive measures may be taken to reduce the incidence according to the existence of risk factors.