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目的探讨肝肺综合征(HPS)的临床特点及常见影响因素。方法回顾性分析我院确诊为乙肝肝硬化的患者临床数据,应用血气分析仪测定其动脉血氧分压。结果乙肝肝硬化患者89例,其中23例合并HPS,发生率25.84%。肝硬化患者并发HPS与杵状指、发绀、黄疸、肝掌、蜘蛛痣、肝性脑病、腹水、门静脉增宽和消化道出血等无关(P>0.05);与并发肝肾综合症(χ2=7.432,P=0.006)、发绀(χ2=3.543,P=0.06)和Child-pugh分级有关(χ2=0.914,P=0.010)。结论临床上Child-pughB级和C级肝硬化中并发肝肾综合征、发绀的患者须注意HPS的发生,应及时并采取相应的治疗措施。
Objective To investigate the clinical features and common factors of hepatopulmonary syndrome (HPS). Methods The clinical data of patients diagnosed with hepatitis B cirrhosis in our hospital were retrospectively analyzed. The arterial oxygen pressure was measured by blood gas analyzer. Results 89 patients with hepatitis B cirrhosis, of which 23 patients with HPS, the incidence rate of 25.84%. Patients with cirrhosis complicated with HPS had no correlation with clubbing, cyanosis, jaundice, liver palms, spider nevus, hepatic encephalopathy, ascites, portal vein widening and gastrointestinal bleeding (P> 0.05) 7.432, P = 0.006), cyanosis (χ2 = 3.543, P = 0.06) and Child-pugh classification (χ2 = 0.914, P = 0.010). Conclusions In patients with hepatorenal syndrome and Child-pugh class B and C cirrhosis, patients with cyanosis should pay attention to the occurrence of HPS, and should take timely and appropriate treatment.