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目的:研究急性心力衰竭(AHF)患者急救后的生存获益情况。方法:回顾性分析182例AHF患者急诊急救开始到之后4h内接受的急救情况以及随访3个月的生存情况,评估急救后患者的生存获益情况。结果:急救治疗后总有效率为92.31%,病死率为2.75%;急救后与急救前舒张压、收缩压、心率以及血氧饱和度比较,差异有统计学意义(P<0.01)。血浆N末端B型利钠肽原(NT-proBNP)水平与左室射血分数呈显著的负相关(r=-0.57,P<0.01);肽素与年龄呈显著的正相关(r=0.18,P<0.05);二者与NYHA心功能分级均呈显著的正相关(r值分别为0.50、0.28,P<0.01)。结论:AHF患者接受科学合理的急救措施有助于其生命体征的恢复。血浆NT-proBNP水平和肽素水平可对患者急救后的生存获益价值进行有效的评估。
Objective: To investigate the survival benefit of emergency patients after acute heart failure (AHF). Methods: A retrospective analysis of 182 cases of emergency treatment of AHF emergency start within 4h after receiving the first aid and survival were followed up for 3 months to assess the survival benefit of patients after first aid. Results: The total effective rate after first aid treatment was 92.31% and the case fatality rate was 2.75%. There was significant difference in diastolic blood pressure, systolic blood pressure, heart rate and oxygen saturation before and after first aid (P <0.01). There was a significant negative correlation between plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) and left ventricular ejection fraction (r = -0.57, P <0.01) , P <0.05). There was a significant positive correlation between NYHA class and NYHA functional class (r = 0.50,0.28, P <0.01). Conclusion: AHF patients receiving scientific and reasonable first aid measures help to restore their vital signs. Plasma NT-proBNP levels and copeptin levels can be useful in assessing the survival benefit of patients after first aid.