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[目的]评估2012年河北省肿瘤登记地区恶性肿瘤发病与死亡情况。[方法]收集2012年河北省9个肿瘤登记地区上报的恶性肿瘤发病与死亡资料,分地区(城市/农村地区)、性别、年龄别和部位计算恶性肿瘤发病率、死亡率,前10位恶性肿瘤顺位、构成和累积率;采用2000年中国标准人口构成和Segi’s世界人口构成分别计算中国和世界人口年龄标化发病/死亡率。[结果]2012年河北省9个肿瘤登记地区共覆盖人口4 986 847人(其中城市地区2 098 547人,农村地区2 888 300人)。全省估计新发病例约187 900例(男性101 100例,女性86 800例),死亡约119 800例(男性74 500例,女性45 300例)。河北省肿瘤登记地区恶性肿瘤发病率为258.12/10万,中标率为210.65/10万,世标率为208.50/10万,累积率(0~74岁)为24.46%。城市地区恶性肿瘤发病率为256.99/10万,估计新发病例约为87 600例;农村地区发病率为258.94/10万,估计新发病例约为100 300例。河北省肿瘤登记地区恶性肿瘤死亡率为164.63/10万,中标率为137.30/10万,世标率为137.39/10万,累积率(0~74岁)为14.58%。估计城市和农村地区恶性肿瘤死亡病例分别为55 000例和64 800例。农村地区死亡率(167.16/10万)高于城市地区死亡率(161.16/10万)。肺癌、胃癌、乳腺癌、食管癌、肝癌和结直肠癌是河北省常见的恶性肿瘤,前10位恶性肿瘤约占全部新发病例的72.31%。肺癌、胃癌、肝癌、食管癌和结直肠癌是威胁河北省居民生命健康的主要恶性肿瘤,前10位恶性肿瘤约占死亡病例的75.24%。[结论]肺癌、胃癌、食管癌、乳腺癌、肝癌、结直肠癌是河北省主要恶性肿瘤,加强癌症筛查及早诊早治,降低主要恶性肿瘤的发病率与死亡率是河北省当前的重要任务。
[Objective] To evaluate the incidence and mortality of malignant tumors in cancer registration areas in Hebei Province in 2012. [Methods] The incidences and deaths of malignant tumors reported in 9 tumor registration areas of Hebei province were collected in 2012, and the incidences of malignant tumors, the incidence of death, the top 10 malignant tumors were calculated by region, city and country, sex, age and location Tumor location, composition and cumulative rate; age-standardized morbidity / mortality of China and the world population were calculated respectively by China’s standard population in 2000 and Segi’s world population. [Results] A total of 4 986 847 people were covered in 9 tumor registration areas in Hebei Province in 2012 (including 2 098 547 in urban areas and 2 888 300 in rural areas). The province estimates about 187 900 new cases (101 100 males and 86 800 females) and about 119 800 deaths (74 500 males and 45 300 females). The incidence rate of malignant tumor in the tumor registration area of Hebei Province was 258.12 / 100000, the successful rate was 210.65 / 100000, the world standard rate was 208.50 / 100000, and the accumulative rate (0-74 years) was 24.46%. The prevalence of malignant tumors in urban areas was 256.99 / 100 000, with an estimated 87 600 new cases. The incidence in rural areas was 258.94 / 100 000 and an estimated 100 300 new cases were found. The death rate of malignant tumor in the tumor registration area of Hebei Province was 164.63 / 100000, the successful rate was 137.30 / 100000, the world standard rate was 137.39 / 100000, and the accumulative rate (0-74 years) was 14.58%. The estimated number of deaths from malignancies in urban and rural areas are 55 000 and 64 800, respectively. Mortality in rural areas (167.16 / 100,000) is higher than in urban areas (161.16 / 100,000). Lung cancer, gastric cancer, breast cancer, esophageal cancer, liver cancer and colorectal cancer are common malignancies in Hebei Province. The top 10 malignant tumors account for 72.31% of all new cases. Lung cancer, gastric cancer, liver cancer, esophageal cancer and colorectal cancer are the major malignant tumors that threaten the life and health of Hebei residents. The top 10 malignant tumors account for about 75.24% of the deaths. [Conclusion] Lung cancer, gastric cancer, esophageal cancer, breast cancer, liver cancer and colorectal cancer are the major malignant tumors in Hebei Province. To strengthen cancer screening and early diagnosis and early diagnosis and treatment, reducing morbidity and mortality of major malignant tumors is currently important in Hebei Province task.