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本文对62例原发性肾病综合征激素敏感型患儿,检测其血清皮质醇浓度共74例次,结果表明:肾病初发与复发患儿血皮质醇浓度低于对照组;缓解期频繁复发患儿血皮质醇浓度低于非频繁复发患儿(P<0.001)。停药期两组患儿血皮质醇浓度恢复正常。38例做ACTH兴奋试验均呈正常反应。提示缓解期肾上腺皮质功能恢复缓慢可能是肾病频繁复发的重要原因之一。
In this paper, 62 cases of primary nephrotic syndrome hormone-sensitive children, the detection of serum cortisol concentration of a total of 74 cases, the results showed that: the incidence of nephropathy in children with recurrent cortisol lower than the control group; recurrent frequent remissions Children with cortisol concentrations were lower than those with infrequent recurrence (P <0.001). Corticosteroid concentrations returned to normal in both groups during the withdrawal period. 38 cases of ACTH excited test showed normal reaction. Suggesting that slow recovery of adrenal cortex may be one of the important reasons for frequent recurrence of nephropathy.