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目的 :通过对 2 9例恶性胸腺瘤的临床分析 ,评估不同分期胸腺瘤与预后的关系。方法 :分析1985年 2月至 1995年 3月本科收治的 95例胸腺瘤患者。按 Masaoka分期法进行分期 , 期 6 6例(6 9.5% ) , 期 11例 (11.6 % ) , 期 15例 (15.7% ) , 期 3例 (3.2 % )。 、 、 期均为恶性胸腺瘤 ,共2 9例。其中合并重症肌无力 7例 (2 4 .1% )。结果 :随访到 2 6例 ,10年生存率为 37.5% ,其中 期患者 10年生存率为 4 2 .8% , 期为 35.6 % , 期为 0 ,说明预后和肿瘤分期有关。结论 :恶性胸腺瘤诊断仍需依靠临床 -病理结合判断。其治疗原则应尽可能广泛切除肿瘤 ,以达到缓解症状 ,延长生存时间的目的。术后辅以放疗可明显提高生存率
Objective : To evaluate the relationship between different stages of thymoma and prognosis by clinical analysis of 29 cases of malignant thymoma. METHODS: A total of 95 patients with thymoma who underwent the study from February 1985 to March 1995 were analyzed. According to the Masaoka staging method, there were 6 6 cases (6 9.5%), 11 cases (11.6 %), 15 cases (15.7%), and 3 cases (3.2%). The 、 、 period are malignant thymoma, a total of 29 cases. Among them, 7 patients with myasthenia gravis (24.1%) were included. Results: A total of 26 patients were followed up. The 10-year survival rate was 37.5%. The 10-year survival rate was 42.8%, the period was 35.6 %, and the period was 0. It indicated that the prognosis was related to the tumor stage. Conclusion: The diagnosis of malignant thymoma still needs to rely on clinical-pathological combined judgment. The principle of treatment should be as extensive as possible to remove the tumor in order to relieve symptoms and prolong survival time. Supplementation with radiotherapy after surgery can significantly improve the survival rate