通过检测32例结直肠癌患者术前外周血免疫抑制酸性蛋白（IAP）、白细胞总数、中性粒细胞（N）、淋巴细胞（L）及中性粒细胞与淋巴细胞比值（N／L），发现随结直肠癌病期进展，IAP含量、N及N／L随之增高，L下降。IAP含量与N／L比值变化呈直线相关关系。提示结直肠癌患者外周血IAP含量、N／L比值有助于术前病期的估计，也对结直肠癌的治疗及预后判断有一定意义。 Detected preoperative serum immunosuppressive acid protein (IAP), total leukocyte count, neutrophil (N), lymphocyte (L), and neutrophil-lymphocyte ratio (N/L) in 32 patients with colorectal cancer. It was found that with the progression of colorectal cancer, IAP content, N, and N/L increased, and L decreased. There is a linear correlation between the IAP content and the N/L ratio change. It is suggested that the IAP content and the N/L ratio of peripheral blood in patients with colorectal cancer contribute to the estimation of the preoperative stage, and also have a certain significance for the treatment and prognosis of colorectal cancer.