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本文应用滤纸干血滴酶联允疫吸附试验(ELISA)对山东部分城市农村地区149例10岁以内唇腭裂患儿进行弓形体抗体检测,阳性率为30.2%;其中1岁以内患儿66人,阳性率为25.76%,而1岁内正常健康小儿阳性率为6.25%,两组间阳性率有非常显著的意义(P<0.01)。提示弓形体感染可能是辱腭裂发生的不可忽视的因素之一。
In this paper, 149 cases of cleft lip and palate children with cleft lip and palate within 10 years of age in urban areas of Shandong Province were tested for Toxoplasma gondii antibody by filter paper dry blood enzyme linked immunosorbent assay (ELISA), the positive rate was 30.2%; 66 children , The positive rate was 25.76%. The positive rate of normal healthy children in 1 year old was 6.25%. There was a significant positive rate between the two groups (P <0.01). Tip Toxoplasma gonorrhoeae infection may be one of the factors that can not be ignored.