Na_3CaDTPA 一直用以促排体内的超铀元素和其它一些金属。其使用禁忌症是心血管系统疾患、肾疾患、顽固性的造血抑制和妊娠。所以,人们对于长期使用时促排效力与Na_3Ca-DTPA 相似而毒性(对胚胎、细胞、肾脏)较低的Na_3ZnDTPA 发生兴趣。然而,已知在超铀元素进入血液后最初几小时内,使用Na_3Zn-DTPA 的促排效果低于Na_3CaDTPA 的;若在大鼠注射~(239)Pu 后一个月才使用大剂量(500μ- Na_3CaDTPA has been used to promote body transuranics and other metals. Its use contraindications are cardiovascular system disorders, kidney disorders, refractory hematopoietic suppression and pregnancy. Therefore, people are interested in promoting Na_3ZnDTPA, which is similar in toxicity and low in toxicity (on embryo, cell and kidney), to Na_3Ca-DTPA when used for a long time. However, it is known that the use of Na_3Zn-DTPA is less effective than Na_3CaDTPA in the first few hours after the transuranics enter the blood; if a large dose (500μ-