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钩端螺旋体病(以下简称钩体病)是四川省常见病之一,发病时间集中在秋收季节,农民因下田劳动受染,1980～1989年呈现暴发流行达94县次。肺弥漫性出血(以下简称PDH)是导致四川省钩体病患者死亡的主要原因,占该病死因的98％。经过多年现场观察发现PDH的发生发展有严格规律性,独特的临床征象和病理变化,是一种国内外文献未系统报道过的一种临床病理实体(Special clinico-pathological entity)。通过乐山市几个县长期现场研究,及实验室研究,发现PDH是由数量多、毒力强、致病力大的钩体引起的,在四川、贵州、湖南、湖北
Leptospirosis (hereinafter referred to as leptospirosis) is one of the common diseases in Sichuan Province. The onset time is concentrated in the autumn harvest season. Peasants were infected with Shimoda labor and the outbreak spread from 1980 to 1989 reached 94 counties. Diffuse pulmonary hemorrhage (hereinafter referred to as PDH) is the leading cause of death in patients with leptospirosis in Sichuan Province, accounting for 98% of the cause of death. After years of field observation, PDH has been found to have strict regularity and unique clinical signs and pathological changes. It is a clinically clinically-specific clinical pathology entity not reported systematically in China and abroad. Through the long-term field research and laboratory research in several counties of Leshan City, PDH was found to be caused by a large number of virulent virulent leptospirosis strains in Sichuan, Guizhou, Hunan and Hubei provinces