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目的分析妊娠20周前孕妇TORCH的感染状况,为该地区人口优生优育提供参考依据。方法采用电化学发光免疫分析法检测2 002例妊娠20周前的孕妇血清TORCH抗体,并对其检测结果进行统计分析。结果 TOX-Ig M、RUV-Ig M、CMV-Ig M的阳性率分别为0.85%、0.80%、1.05%,阳性率之间的差异无统计学意义。TOX-Ig G、RUV-Ig G、CMV-Ig G、HSV-1-Ig G、HSV-2-Ig G的阳性率分别为14.29%、86.01%、98.30%、80.57%、8.19%,CMV-Ig G的阳性率最高(P<0.01)。36～45岁孕妇的TOX-Ig M阳性率明显高于18～25岁和26～35岁年龄组(P<0.01)。RUV-Ig M和CMV-Ig M的阳性率在各年龄组间无统计学差异(P>0.05)。不同的季节TOX-Ig M、RUV-Ig M、CMV-Ig M的阳性率无统计学差异(P>0.05)。结论该地区孕妇弓形虫的感染具有年龄的差异,季节对孕妇TORCH感染的影响无统计学意义。由于TORCH感染是不良妊娠结局的危险因素,因此育龄妇女在孕前和孕早期进行TORCH检测对于优生优育尤为重要。
Objective To analyze the status of TORCH infection in pregnant women before 20 weeks of gestation, and provide reference for population prenatal and postnatal care in this area. Methods The serum TORCH antibodies of 2 002 pregnant women before pregnancy were detected by electrochemiluminescence immunoassay, and the results were statistically analyzed. Results The positive rates of TOX-Ig M, RUV-Ig M and CMV-Ig M were 0.85%, 0.80% and 1.05%, respectively. There was no significant difference between the positive rates. The positive rates of TOX-Ig G, RUV-Ig G, CMV-Ig G, HSV-1-Ig G and HSV-2-Ig G were 14.29%, 86.01%, 98.30%, 80.57%, 8.19% The highest positive rate of Ig G (P <0.01). The positive rate of TOX-Ig M in 36-45 years old pregnant women was significantly higher than that in 18-25 years old and 26-35 years old group (P <0.01). The positive rates of RUV-Ig M and CMV-Ig M were not significantly different among all age groups (P> 0.05). There was no significant difference in the positive rates of TOX-Ig M, RUV-Ig M and CMV-Ig M in different seasons (P> 0.05). Conclusion Toxoplasma gondii infection in pregnant women in this area is different in age. There is no significant difference in seasons between the two groups. Since TORCH infection is a risk factor for adverse pregnancy outcomes, TORCH testing in pre-pregnancy and early-pregnant women is particularly important for prenatal and postnatal care.