近年来许多学者,对机体内各器官组织中的40余种在形态、组织化学,功能相似的细胞进行了深入的研究。1968年英国伦敦大学 Pearse 教授,根据产肽类激素细胞的组织化学和超微结构的特点,提出 APUD 系统的概念.APUD(Amine Precursor Uptake andDecarboxylation)细胞系统。其原意为能够富集生物胺前体氨基酸,并能进行脱羧的细胞称为 APUD 系统,这些细胞除可分泌胺类外,大部分可分泌肽类激素.取其为首的字母 AP In recent years, many scholars have conducted in-depth studies on more than 40 kinds of cells with similar morphological, histochemical and functional characteristics in various organs and tissues in the body. In 1968 Professor Pearse from University of London, UK, proposed the concept of APUD system based on the histochemical and ultrastructural features of peptide-producing hormone-like cells, and the APUD (Amine Precursor Uptake and Decarboxylation) cell system. The original intention is to enrich biogenic amine precursor amino acids, and can be decarboxylated cells called APUD system, in addition to these cells can secrete amines, the majority of secreted peptide hormones .Attending the letter headed by AP