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二丁基苯基磷酸盐()用作增塑剂,是一种透明、无色油质溶液,不溶于水,易溶于有机溶剂。灌胃给药LD_(50)小鼠为1790 mg/kg,大鼠为2,140 mg/kg。无明显蓄积作用。在实验结束后进行形态学检查表明,实质性脏器有反应性变化,肝、肾出现淋巴样细胞浸润,脾发生淋巴滤泡增生。将涂抹家兔皮肤,发生皮肤脱屑、皲裂,滴入兔眼结膜囊,出现流泪和睑痉挛,经1～2昼夜渐消退。将鼠尾浸入中,引起动物中毒和死亡,无变应性作用。为了阐明的可能的脱髓鞘作用,给予1.5～2 kg公鸡一次灌胃1g/kg,经2周全部给药公鸡都出现不稳的摇摆步态,然后变跛,最后瘫痪。形态学检查表明,大脑
Dibutylphenyl phosphate () is used as a plasticizer and is a clear, colorless, oily solution that is insoluble in water and soluble in organic solvents. The LD 50 mice administered orally were 1790 mg / kg for rats and 2,140 mg / kg for rats. No significant accumulation effect. Morphological examination at the end of the experiment showed that there were reactive changes in the real organs, lymphoid infiltration in the liver and kidney, and lymphoid follicular hyperplasia in the spleen. Rabbit skin will be smeared, skin desquamation occurs, chapped, drip into the conjunctiva of rabbit eyes, there Tears and blepharospasm, 1 ~ 2 day and night subsided. The rat tail immersed in, causing animal poisoning and death, no allergic effects. In order to clarify the possible demyelination, given 1.5 ~ 2 kg rooster a gavage 1g / kg, after 2 weeks of all the cocks have instability swing gait, and then become lame, and finally paralyzed. Morphological examination showed that the brain