目的甲状腺９９ｍＴｃ－ＭＩＢＩ显像鉴别甲状腺单发，实性或囊实性冷结节的性质。方法３３例甲状腺单发、实性或囊实性冷结节病人采用９９ｍＴｃ－ＭＩＢＩ显像检查，全部病例均经手术及病理证实。结果恶性肿瘤诊断灵敏度为８００％，特异性７５０％，准确率为７５０％。结论该项检查方法对甲状腺孤立、冷结节的良恶性鉴别有一定价值，可帮助临床医生参考确定哪些病人应及时手术。 Objective Thyroid 99mTc-MIBI scintigraphy was used to distinguish the characteristics of thyroid solitary, solid or cystic cold nodules. Methods Thirty-three cases of thyroid glands with solid or solid cystic cold nodules were examined with 99mTc-MIBI. All cases were confirmed by surgery and pathology. Results The diagnostic sensitivity of malignant tumor was 800%, specificity 750%, and accuracy rate was 750%. Conclusion This test method has certain value for the differential diagnosis of benign and malignant thyroid gland isolates and cold nodules. It can help clinicians to determine which patients should undergo surgery in time.