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目的 :探讨硝酸铈对 Hep- 2喉癌细胞体外增殖生长的影响。方法 :在硝酸铈浓度为 0 .0 5～ 3.2 mm ol/ L 的培养条件下 ,采用 MTT实验方法检测喉癌生长抑制率并测定喉癌细胞的克隆形成率。结果 :0 .4～ 3.2 m mol/ L 范围内 ,硝酸铈表现为提高喉癌细胞生长抑制率与降低其克隆形成率。结论 :硝酸铈在体外培养中对喉癌细胞增殖有一定的抑制作用
Objective: To investigate the effect of cerium nitrate on proliferation and proliferation of Hep-2 laryngeal carcinoma cells in vitro. Methods: The growth inhibition rate of laryngeal carcinoma was detected by MTT assay and the colony formation rate of laryngeal carcinoma cells was determined under the condition of cerium nitrate concentration of 0.05 ~ 3.2 mm ol / L. Results: In the range of 0.4 ~ 3.2 m mol / L, cerium nitrate increased the growth inhibition rate and decreased the clonogenic rate of laryngeal carcinoma cells. Conclusion: Cerium nitrate inhibits the proliferation of laryngeal carcinoma cells in vitro