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【目的】探讨电视胸腔镜(VATS)、微创小切口及常规开胸对患者围术期肺功能的影响。【方法】回顾性分析本院胸心外科2011年10月至2014年7月收治的100例肺叶切除术患者的临床资料,根据手术路径分为VATS 组(30例)、微创小切口组(34例)、开胸手术组(36例),比较三组患者术前术后的肺功能指标变化情况。【结果】三组患者的术前 FVC、FEV1、MVV、PEF 测定值差异不具有统计学意义(P >0.05)；术后 d1、d3、d5、d7的FVC、FEV1、MVV、PEF 测定值比较差异具有统计学意义(P 0.05),术后 d5、d7 VATS 组的 PaO 2显著地高于微创小切口组和开胸手术组,PaCO 2测定值显著低于微创小切口组和开胸手术组(P 0.05);postoperative,1,3,5,and 7d of FVC,FEV1,MVV,PEF measured values were measured and the differences were statistically significant (P 0.05),however,5 and 7d postoperative,PaO2 values of the VATS group were significantly higher than those of the other two groups.the VATS group PaO2 after the first minimally invasive group 5,7d and thoracotomy group,PaCO2 measured values were significantly lower than those of the other two groups minimally invasive thoracic surgery group and group (P <0.05).[Conclusion]Implemented using The use of VATS lobectomy has a smaller effect on lung function and blood gas index of patients than the on the more minimally invasive and conventional thoracotomy lo-bectomy.small,The differences between minimally invasive and conventional thoracotomy lobectomy for lung function and blood gas index the impact is insignificant.