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目的 探讨膀胱癌相关尿道癌的发生原因、预防及处理原则。方法 分析 11例与膀胱癌相关尿道癌的临床病理资料 ,3例为膀胱多发癌累及后尿道 ,1例为膀胱癌发生盆腔广泛浸润转移侵犯尿道 ,7例为全膀胱切除术后出现尿道癌。结果 全膀胱切除术后尿道癌发生率 2 3.8% ,2例行全膀胱切除 +回肠膀胱术 +全尿道切除术 ,1例行经尿道膀胱肿瘤电切 ,1例盆腔广泛转移者行放射治疗 ,7例全膀胱切除术后尿道癌者补行全尿道切除术。结论 膀胱癌术后尿道癌重在预防 ;全膀胱切除术后选择回肠膀胱术及尿流改道 ,须同时行全尿道切除术 ;选择原位新膀胱 +下尿路重建术者 ,术后需密切随访观察
Objective To investigate the causes, prevention and treatment of bladder cancer related urethral carcinoma. Methods The clinicopathological data of 11 cases with bladder cancer were retrospectively analyzed. Among them, 3 cases of multiple bladder cancer involving the posterior urethra, 1 case of bladder cancer extensive pelvic invasion and invasion of urethra, and 7 cases of urethral cancer after total cystectomy. Results The incidence of urethral cancer after total cystectomy was 3.8%. Two cases underwent total cystectomy, ileal bladder surgery and total urethral resection. One case underwent transurethral resection of bladder tumor and one case underwent extensive radiotherapy. Seven cases of total cystectomy urethral cancer make full urethral resection. Conclusions The postoperative urethral carcinoma of the bladder is the most important prophylaxis. Cholecystectomy and ileal diversion after total cystectomy should be treated with total urethral resection. The patients who underwent neobladder or urinary reconstruction should be close Follow-up observation