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刚地弓形虫有三种基因型,但感染小鼠的急性毒力仅见于Ⅰ型(以RH株为代表)。已知SAG1是编码弓形虫速殖子主要表面抗原的单拷贝基因,位于虫体8号染色体,多项研究表明SAG1参与速殖子吸附、侵入宿主细胞。先前的研究发现SAG1位点上一个特
Toxoplasma gondii has three genotypes, but acute virulence in infected mice is found only in type I (represented by RH strain). SAG1 is known to encode a single copy of the major surface antigen of tachyzoites Toxoplasma gondii, located on chromosome 8 and many studies have shown that SAG1 is involved in tachytrophic adsorption and invading host cells. Previous studies found a special SAG1 locus