白细胞介素８（ＩＬ－８）是在８０年代后期发现的一种细胞因子，对Ｔ淋巴细胞、中性粒细胞、嗜碱性粒细胞有较强的趋化作用，在炎症反应及免疫调节中起重要作用。最近发现肾小球系膜细胞和肾小管上皮细胞可产生ＩＬ－８。本文介绍了ＩＬ－８在肾小球肾炎、尿路感染、肾病综合征、血液透析和腹膜透析中的水平变化和意义。 Interleukin-8 (IL-8) is a cytokine found in the late 1980s that has a strong chemotactic effect on T lymphocytes, neutrophils, and basophils. It has been shown to play an important role in inflammation and immunoregulation Play an important role. Recently, glomerular mesangial cells and tubular epithelial cells were found to produce IL-8. This article describes the changes and significance of IL-8 in glomerulonephritis, urinary tract infection, nephrotic syndrome, hemodialysis and peritoneal dialysis.