目的　探讨催乳素垂体腺瘤经蝶显微手术的治疗效果。方法　总结 119例催乳素垂体腺瘤采取经蝶显微手术治疗的安全性与远期疗效。本组女 10 7例 ,男 12例。年龄13～ 56 (平均 36 .7)岁。术前均经CT扫描或MRI确诊 ,其中大腺瘤 15例 (12 .6 1% ) ,微腺瘤10 4例 (87.4 % )。手术采取经唇下 -鼻中隔 -蝶窦入路或经鼻前庭 -鼻中隔 -蝶窦入路行肿瘤切除术。结果　术后并发症少 ,无死亡。 10 3例 (86 .6 % )行随访观察 ,随访期 6月～ 7.5年 (平均 3.5年 ) ,88例 (85.4 % )获治愈效果。结论　采用经蝶显微手术切除本型肿瘤是一种安全、有效的治疗方法 Objective To investigate the therapeutic effect of prolactin pituitary adenoma by microsurgical microsurgery. Methods Summarize the safety and long-term efficacy of 119 patients with prolactin pituitary adenoma treated with transsphenoidal microsurgery. The group of female 107 cases, 12 males. Age 13 ~ 56 (average 36.7) years old. Preoperative CT scan or MRI confirmed, including 15 cases of adenoma (12.61%), 104 cases of microadenomas (87.4%). Surgical resection via lip - nasal septum - sphenoid sinus approach or nasal vestibule - nasal septum - sphenoid sinus approach. Results less postoperative complications, no death. One hundred and three patients (86.6%) were followed up for 6 months to 7.5 years (average 3.5 years), and 88 patients (85.4%) were cured. Conclusions This technique is a safe and effective treatment for this type of tumor by transsphenoidal microsurgery