绿脓杆菌是临床上难以对付的病原菌,尤其当绿脓杆菌对氨基糖甙类抗生素产生耐药时,则更难治愈,往往会导致病人死亡。常用的治疗绿脓杆菌的β-内酰胺抗生素有α-羧基青霉素,例羧苄霉素,替卡西林等。这类抗生素在临床上呈中等程度的抗绿脓杆菌的活力,且使用剂量相当大,引起了各种毒副反应。近年来经各国科学工作者连续 Pseudomonas aeruginosa is clinically difficult to deal with pathogens, especially when Pseudomonas aeruginosa resistant to aminoglycoside antibiotics, it is more difficult to cure, often leading to patient death. Common treatment of Pseudomonas aeruginosa β-lactam antibiotics are α-carboxy penicillin, such as carbenicillin, ticarcillin and so on. These antibiotics are clinically moderate anti-Pseudomonas aeruginosa activity, and the use of a considerable dose, causing a variety of toxic and side effects. In recent years by the continuous scientific scientists in various countries