γ-谷氨酰转肽酶(γ-GT)是广泛分布于哺乳动物组织,催化谷胱甘肽分解的起始酶,对于氨基酸的转运起重要作用。近年来人们的注意力集中到该酶与原发性肝癌和化学致癌剂诱导的肝癌发病关系上,许多学者已把它视为肝癌诊断的标志酶。谷口等发现由于内源性抑制剂或激活剂的存在,该酶在血液中存在有活性型和非活性型,故酶活性不能反映出真实的酶蛋白量。为了能更正确、更敏 Gamma-glutamyl transpeptidase (γ-GT) is widely distributed in mammalian tissues and catalyzes the initiation of glutathione decomposition, which plays an important role in the transport of amino acids. In recent years, people’s attention has focused on the relationship between this enzyme and primary hepatocarcinoma and chemical carcinogen-induced hepatocellular carcinoma. Many scholars have regarded it as a marker enzyme for the diagnosis of liver cancer. Taniguchi found that due to the presence of endogenous inhibitors or activators, the enzyme exists in the blood of active and inactive type, so the enzyme activity does not reflect the true amount of enzyme protein. In order to be more correct, more sensitive