目的:对比观察塞来昔布及艾灸治疗骨性关节炎的疗效。方法:选取60例骨性关节炎患者,随机分为治疗组和对照组。治疗组给予口服塞来昔布200mg,1次/d;对照组给予艾灸治疗,共治疗6周。分别观察各组的疗效指标和不良反应发生率。结果:塞来昔布与艾灸均有较好的治疗效果,但艾灸经济实用,且安全副作用少。结论:艾灸治疗是一种临床治疗骨性关节炎有效、安全的非药物治疗,操作简单,特别实用基层工作者。 Objective: To compare the efficacy of celecoxib and moxibustion in the treatment of osteoarthritis. Methods: Sixty patients with osteoarthritis were randomly divided into treatment group and control group. The treatment group was given oral celecoxib 200mg, 1 / d; control group was given moxibustion treatment for a total of 6 weeks. The efficacy of each group were observed and the incidence of adverse reactions. Results: Celecoxib and moxibustion have better therapeutic effect, but moxibustion is economical and practical with few safety side effects. Conclusion: Moxibustion is an effective and safe non-drug treatment for clinical treatment of osteoarthritis. It is easy to operate and is especially practical for grassroots workers.