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在某些哺乳类动物中,可观察到分娩前子宫肌层呈静止状态,这时血浆中可测到高水平的松弛素。有证据表明,该激素对子宫肌肉有直接的抑制作用。另外,松弛素通过抑制催产素的释放也可引起子宫肌层的静止。为了确定松弛素是否通过中枢神经作用而抑制催产素的释放,作者通过对麻醉的哺乳大鼠静脉注射猪松弛素观察对射乳的影响。实验结果表明,不同的注射剂量,反射性射乳受到不同程度的抑制;并且
In some mammals, the myometrium is observed as a quiescent state before delivery, when high levels of relaxin are detected in the plasma. There is evidence that the hormone has a direct inhibitory effect on the uterine muscles. In addition, relaxin can also cause the myometrium to rest by inhibiting the release of oxytocin. To determine if relaxin inhibits the release of oxytocin via CNS effects, we investigated the effect of injecting porcine relaxin on anesthetized lactating rats. The experimental results show that the different injection dose, reflex breast milk to varying degrees of inhibition; and