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分子的立体构型是其原子在空间的排布方式。确定分子的构型对于立体化学、反应历程、生理活性物质的功能以及药物的生理作用等方面的研究都具有重大意义,含有手性中心的化合物都具有旋光性,它们的对映体的空间构型常用两种方法标记:D、L法和R、S法。本世纪五十年代以前,旋光异构体的构型用D、L法。由于它是与标准物的构型相联系或对照得到的构型,故为一种相对构型方法。在已经取得构型联系的各类化合物中,特别是在糖类
The three-dimensional configuration of a molecule is the arrangement of its atoms in space. Determining the configuration of a molecule is of great significance for the study of stereochemistry, reaction processes, the function of physiologically active substances, and the physiological effects of drugs. The compounds containing chiral centers are all optically active and their enantiomeric spaces Two commonly used type of mark: D, L method and R, S method. Before the fifties of this century, the configuration of optical isomers using D, L method. Because it is associated with the configuration of the standard or control the configuration obtained, it is a relative configuration method. Among the various classes of compounds that have made a conformational link, especially sugars