Synthesis and Crystal Structure of 1′-Methyl-4′- (4-chlorophenyl)-1H-indole-3-spiro-2′-pyrrolidine-

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The title compound (C26H20ClN3O3) has been synthesized by 1,3-dipolar cycloaddition reaction from isatin, sarcosine and (Z)-4-(4-chlorobenzylidene)-2-phenyloxazol-5(4H)-one through a one-pot procedure, and its structure was confirmed by IR, 1H NMR, elemental analysis and single-crystal X-ray diffraction analysis. The crystal belongs to the triclinic system, space group P1, with a = 9.3903(19), b = 11.398(2), c = 12.603(3) , α = 83.495(3), β = 68.988(3), γ = 67.178(3)°, V = 1160.1(4) 3, Z = 2, Mr = 457.90, Dc = 1.311 g/cm3, μ = 0.198 mm-1, F(000) = 476, the final R = 0.0489 and wR = 0.1144 for 3109 observed reflections with I > 2σ(I). The title compound (C26H20ClN3O3) has been synthesized by 1,3-dipolar cycloaddition reaction from isatin, sarcosine and (Z) -4- (4-chlorobenzylidene) -2-phenyloxazol- , and its structure was confirmed by IR, 1H NMR, elemental analysis and single-crystal X-ray diffraction analysis. The crystal belongs to the triclinic system, space group P1 with a = 9.3903 (19), b = 11.398 , c = 12.603 (3) , α = 83.495 (3), β = 68.988 (3), γ = 67.178 (3) °, V = 1160.1 (4) 3, Z = 2, Mr = 457.90, Dc = 1.311 g / cm3, μ = 0.198 mm-1, F (000) = 476, the final R = 0.0489 and wR = 0.1144 for 3109 observed reflections with I> 2σ (I).
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