论文部分内容阅读
测定混合制剂Tricofuran 中硝呋甲肟和呋喃唑酮的已有方法较麻烦费时,且分析时间长会造成药物的分解。作者采用改良的Vierordt法(吸收度比法)同时测定此二成分。本法不需予先分离,可直接进行测定,方法简便快速。硝呋甲肟和呋喃唑酮的平均回收率分别为99.50±1.59%和100.20±1.16%(P=0.05)。取相当于每一化合物约50~80mg 的tricofuran粉(外用)或tricofuran阴道栓精密秤定,于小烧杯中用二甲基甲酰胺捣拌提取三次(每次用15ml)。转移
Existing methods for the determination of nifedipine and furazolidone in the mixed formulation Tricofuran are cumbersome and time consuming, and the long analysis time can cause the drug to decompose. The authors used the modified Vierordt method (absorption ratio method) to determine these two components simultaneously. This method does not require prior separation, can be directly measured, the method is simple and quick. The mean recoveries of nifedipine and furazolidone were 99.50 ± 1.59% and 100.20 ± 1.16%, respectively (P = 0.05). Take about 50 ~ 80mg of tricofuran powder (external use) or tricofuran vaginal suppository, which is equivalent to about 50 ~ 80mg of each compound, and mix them in small beaker three times with 15ml each. Transfer