近年来,他汀类药物已从单一的调血脂药,发展成为一类重要的抗动脉粥样硬化的药物,在脑卒中、冠心病、高血压等疾病治疗和一级/二级预防方面也都显示出良好疗效,使他汀类药物焕发青春,迈入新的里程。这些获益大多数是建立在他汀类的强化给药(即早、大、长)的基础之上的。因此,他汀类药物的安全性也是临床上高度关注的问题。 In recent years, statins have evolved from a single lipid-lowering drug to a class of important anti-atherosclerotic drugs and have also been used in the treatment and primary / secondary prevention of stroke, coronary heart disease, hypertension and other diseases It shows a good effect, so that statins glow youth, into a new milestone. Most of these benefits are based on the intensive administration of statins (ie, early, big, long) basis. Therefore, the safety of statins is also a clinically significant issue.