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本文报道了15例儿童系统性红斑狠疮(SLE)。分析了其临床表现、内脏受累及实验改变,并且与17例随机抽取的成年患者进行比较,结果表明儿童SLE的肾脏和心脏损害比成人严重(P<0.05),此外,淋巴细胞转化率降低在儿童患者亦更为普遍(P<0.05)。儿童患者其它器官损害亦多于成人,但统计学上无显著差异。中西医结合治疗效果较为满意。本文还讨论了儿童SLE的发病年龄、性别、临床表现、诊断和治疗等问题。
This article reports 15 cases of children with systemic lupus erythematosus (SLE). The clinical manifestations, visceral involvement and experimental changes were analyzed and compared with those of 17 adult patients randomly selected. The results showed that the renal and cardiac lesions in children with SLE were more severe than those in adults (P <0.05). In addition, the lymphocyte transformation rates were significantly lower in Children are also more common (P <0.05). Other organs in children also suffered more damage than adults, but there was no statistically significant difference. Integrative medicine more satisfactory results. This article also discusses the age, gender, clinical presentation, diagnosis and treatment of childhood SLE.